
Purpose: To investigate the evolution of additive manufacturing in maxillofacial prosthetic rehabilitation from 2000 to 2026 by integrating bibliometric analysis with clinical evidence mapping, emphasizing research trends, technological applications, and the maturity of clinical evidence.
Materials and Methods: Original Scopus-indexed journal articles (2000–2026) were screened for direct or indirect additive manufacturing applications in maxillofacial prosthetic rehabilitation. After full-text assessment, 125 articles were included. Bibliometrix /Biblioshiny summarized publication trends, sources, citations, and bibliographic indicators; VOSviewer was used for co-authorship, country, keyword, bibliographic-coupling, and co-citation networks. Study designs and clinical outcome reporting were independently mapped.
Results: The 125 publications, drawn from 56 sources, received 2,955 Scopus citations; output peaked at 17 articles in 2025. The three leading prosthodontic journals contributed 56 articles (44.8%). The most cited paper received 133 citations. VOSviewer identified 53 recurrent authors, 36 countries, 42 harmonized author keywords, 14 bibliographic-coupling clusters, and five normalized co-citation clusters. Single-patient reports predominated (55.2%), and only seven studies (5.6%) used comparative clinical designs. Patient-reported feedback was confirmed in 37 of 98 clinically oriented reports, with structured instruments in nine and prosthesis follow-up in 29.
Conclusion: Additive manufacturing research in maxillofacial prosthetics has expanded substantially, progressing from technical development toward diverse clinical applications. However, the literature remains dominated by descriptive reports, with limited comparative evidence and inconsistent clinical outcome reporting. (Int J Maxillofac Prosthetics 2026;9:26-39)
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